Botox-Dysport-Azzalure – are commercial names for botulinum toxin type A, produced by Clostridium Botulinum.

Botulinum toxin is a tropism neurotoxin for acetylcholine molecules in the neuromotor plate; therefore, injected into the muscles prevents the nerves from releasing acetylcholine, which is essential in transmitting the nerve impulse from the nerve to the muscle cell.

The result is muscle weakness for a temporary period, until the nerves develop other new terminations that communicate with the muscles.


  • Expression wrinkles: horizontal front wrinkles; vertical wrinkles between eyebrows; external eye corner wrinkles; lower eyelid wrinkles parallel to the ciliary edge; paranasal wrinkles;
  • Drooping mouth corners lift;
  • Outer corner of the eyebrows lift, · platysmal wrinkles; hyperhidrosis.
  • Treatment is outpatient, requires no pre-training, lasts for 15-20 minutes, is not painful; after treatment the patients can immediately return to current activities;
  • The effect is set between 2-10 days, depending on the patient’s metabolism and lasts 4-6 months, after which, if the effect is to be continued, the procedure must be repeated.
  • Botulinum toxin does not create addiction, when the patient decides to stop treatment, the state of the expression wrinkles returns to the start of the treatment.
  • In the case of hyperhidrosis (excessive sweating), in the axillae, palms, treatment is done with local cream anesthesia, lasts between 30-40 minutes, the effect is set between 7-14 days and lasts 8-12 months.
  • Of course, the first step is a consultation where a local exam of the facial wrinkles will be performed and the procedures, indications, contraindications, past medical history, etc. will be discussed thoroughly.

Post-injection indications:

  • Avoid massaging the injected areas;
  • Avoid cosmetic treatment, sauna, hot baths for 7 days
  • Orthostatic or seated position for at least 4 hours
  • Avoid drugs that can interact with botulinum toxin

Facial mimic exercises for 2-3 days to fix the substance are suggested.